Description

1-(4-Chlorobenzyl)-4-(4-(2-(4-Chlorophenoxy)Ethyl)Piperazin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of targeted therapeutic agents. This compound is valued for its complex heterocyclic structure, which serves as a critical building block in modern medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective kinase inhibitors due to its pyrazolo[3,4-d]pyrimidine moiety.
• Oncology Drug Discovery: Used in research programs targeting specific cancer pathways and tumor proliferation mechanisms.
• CNS-Active Compound Synthesis: Employed in creating candidates for neurological and psychiatric disorder treatments.
• Biochemical Tool Compound: Acts as a reference standard or probe in biochemical and pharmacological assays to study enzyme function.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-(4-Chlorobenzyl)-4-(4-(2-(4-Chlorophenoxy)Ethyl)Piperazin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	612523-94-1
Molecular Formula	C24H24Cl2N6O
Molecular Weight	483.39 g/mol
Synonyms	4-[4-[2-(4-Chlorophenoxy)ethyl]-1-piperazinyl]-1-[(4-chlorophenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine; 1-[(4-Chlorophenyl)methyl]-4-[4-[2-(4-chlorophenoxy)ethyl]-1-piperazinyl]pyrazolo[3,4-d]pyrimidine; UNII-6Q6M8H8V8R; 6Q6M8H8V8R; CHEMBL3183457; BDBM50389386; AKOS025310923; ZINC000004143768
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorobenzyl)-4-(4-(2-(4-Chlorophenoxy)Ethyl)Piperazin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.