Description

Phenol, 4-Ethoxy-2,5-Difluoro- is a specialized fluorinated phenolic derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both ethoxy and fluorine substituents, provides precise electronic and steric properties critical for constructing complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies (LCDs).
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, such as polyarylates and polycarbonates, to impart specific thermal and chemical resistance.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Chemical Research: A versatile reagent for academic and industrial R&D in fluorination chemistry and the study of structure-activity relationships (SAR).

Basic Information

Product Name	Phenol, 4-Ethoxy-2,5-Difluoro-
CAS No.	612092-32-7
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	4-Ethoxy-2,5-difluorophenol; 2,5-Difluoro-4-ethoxyphenol; 1-Ethoxy-2,5-difluoro-4-hydroxybenzene; 2,5-Difluoro-4-hydroxyanisole; 4-Hydroxy-2,5-difluorophenyl ethyl ether; 2,5-Difluoro-4-ethoxyphenol; Difluoroethoxyphenol
EINECS	Contact for details

Quality Control

Our Phenol, 4-Ethoxy-2,5-Difluoro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.