Description

(R)-β-n-Acetyl-Phenylalanine Ethyl Ester is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in asymmetric synthesis and peptide chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel Active Pharmaceutical Ingredients (APIs), especially for metabolic and neurological targets.
• Peptidomimetic Synthesis: Used in the design and construction of peptide analogs and mimetics for drug discovery programs.
• Asymmetric Catalysis Research: Serves as a standard or starting material in the development and study of new asymmetric synthetic methodologies.
• Bioconjugation Chemistry: Utilized in the modification of biomolecules, where its acetyl and ester functional groups offer handles for selective reactions.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Fine Chemical Production: A building block for the synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	(R)-β-n-Acetyl-Phenylalanine Ethyl Ester
CAS No.	609849-87-8
Molecular Formula	C₁₃H₁₇NO₃
Molecular Weight	235.28 g/mol
Synonyms	(R)-N-Acetyl-3-phenylalanine ethyl ester; (R)-2-Acetamido-3-phenylpropanoic acid ethyl ester; Ethyl (R)-2-acetamido-3-phenylpropanoate; (R)-Ac-Phe-OEt; (R)-N-Acetylphenylalanine ethyl ester; (R)-α-Acetamidohydrocinnamic acid ethyl ester; (R)-Ethyl 2-acetamido-3-phenylpropionate
EINECS	Contact for details

Quality Control

Our (R)-β-n-Acetyl-Phenylalanine Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.