Description

Ethyl 6-(4-Ethylphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, especially in central nervous system (CNS) and anti-infective research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex fused pyrimido-thiazine ring systems, enabling structure-activity relationship (SAR) studies.
• Research & Development (R&D): Serves as a standard or reference material in analytical method development and pharmacokinetic studies for new molecular entities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional labs for investigating new heterocyclic chemistry and reaction methodologies.

Basic Information

Item	Details
Product Name	Ethyl 6-(4-Ethylphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate
CAS No.	609795-82-6
Molecular Formula	C20H22N2O3S
Molecular Weight	370.47 g/mol
Synonyms	Ethyl 6-(4-ethylphenyl)-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; 7-Carboxy-6-(4-ethylphenyl)-8-methyl-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazin-4-one ethyl ester; 609795-82-6; UNII-8V8S1A8KQN; Pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid derivative; SCHEMBL21806227; DTXSID90648669
EINECS	Contact for details

Quality Control

Our Ethyl 6-(4-Ethylphenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory submission standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.