Description

Isobutyl 6-(2-Bromophenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 609794-68-5. This compound is a key synthetic building block valued for its complex heterocyclic structure, which is integral to the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of new chemical entities, particularly for therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry research.
• API Development: Used in the research and development of new Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Chemical Synthesis Research: Acts as a specialized building block for constructing complex heterocyclic compounds in academic and industrial R&D laboratories.
• Process Chemistry: Employed in route scouting and optimization studies for the scalable production of target molecules.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and niche pharmaceuticals.

Basic Information

Product Name	Isobutyl 6-(2-Bromophenyl)-8-Methyl-4-Oxo-3,4-Dihydro-2H,6H-Pyrimido[2,1-B][1,3]Thiazine-7-Carboxylate
CAS No.	609794-68-5
Molecular Formula	C19H19BrN2O3S
Molecular Weight	435.34 g/mol
Synonyms	Isobutyl 6-(2-bromophenyl)-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate; 2H,6H-Pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid, 6-(2-bromophenyl)-3,4-dihydro-8-methyl-4-oxo-, 1-methylethyl ester; 609794-68-5; Isobutyl 6-(o-bromophenyl)-8-methyl-4-oxo-3,4-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports the stringent requirements of pharmaceutical R&D and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.