Description

2-Trifluoromethyl-Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-value fluorinated pyrimidine building block, a key intermediate in modern synthetic chemistry. Its trifluoromethyl and ester functionalities make it a versatile synthon for constructing complex molecules with enhanced properties. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves bioactivity and environmental stability.
• Material Science Research: Serves as a building block for creating novel fluorinated polymers, liquid crystals, and electronic materials with unique properties.
• Chemical Biology & Proteomics: Employed as a specialty reagent for labeling and modifying biomolecules in drug discovery and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Trifluoromethyl-Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	608517-17-5
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	Methyl 2-(trifluoromethyl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-(trifluoromethyl)-, methyl ester; Methyl 2-trifluoromethylpyrimidine-5-carboxylate; 2-Trifluoromethyl-5-pyrimidinecarboxylic acid methyl ester; 2-(Trifluoromethyl)pyrimidine-5-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.