Description

2,4-Difluoro-6-Methoxybenzaldehyde is a high-purity fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Functional Dye & Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments where the methoxy and difluoro groups modify color and light-fastness properties.
• Cross-Coupling Reactions: The aldehyde group is amenable to further functionalization via reactions like Suzuki, Heck, or reductive amination, enabling rapid library synthesis for drug discovery.
• Ligand & Catalyst Development: Useful for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	2,4-Difluoro-6-Methoxybenzaldehyde
CAS No.	608515-57-7
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	6-Methoxy-2,4-difluorobenzaldehyde; 2,4-Difluoro-6-methoxybenzaldehyde; 2,4-Difluoro-6-methoxy-benzaldehyde; 2,4-Difluoro-6-methoxybenzenecarboxaldehyde; Benzaldehyde, 2,4-difluoro-6-methoxy-; 608515-57-7 (CAS); 6-Methoxy-2,4-difluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2,4-Difluoro-6-Methoxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high purity and consistent quality suitable for sensitive synthesis applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.