Description

4-(4-Methoxyphenoxy)-6-Chloropyrimidine is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyrimidine core functionalized with chlorophenoxy and methoxyphenoxy groups. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides and fungicides with specific modes of action.
• Chemical Synthesis Building Block: Used in cross-coupling reactions and nucleophilic aromatic substitutions to construct more complex heterocyclic systems.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with tailored electronic or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	4-(4-Methoxyphenoxy)-6-Chloropyrimidine
CAS No.	607723-54-6
Molecular Formula	C11H9ClN2O2
Molecular Weight	236.65 g/mol
Synonyms	6-Chloro-4-(4-methoxyphenoxy)pyrimidine; 4-(p-Methoxyphenoxy)-6-chloropyrimidine; 6-Chloro-4-(4-methoxyphenoxy)pyrimidine; 4-(4-Methoxyphenoxy)-6-chloro-pyrimidine; 4-(4-Methoxyphenoxy)-6-chloropyrimidine; 4-(4-Methoxyphenoxy)-6-chloro-pyrimidine; 4-(4-Methoxyphenoxy)-6-chloropyrimidine (CAS 607723-54-6)
EINECS	Contact for details

Quality Control

Our 4-(4-Methoxyphenoxy)-6-Chloropyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.