Description

2(1H)-Pyrimidinone,4-Amino-5-Fluoro-6-(Fluoromethyl)-(9Ci) is a high-value fluorinated pyrimidinone derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and fluoromethyl substituents, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel antiviral and anticancer drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging the fluorine moiety for enhanced activity and stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Manufacturing: Acts as a precursor for other complex fluorinated organic molecules used in material science and electronics.
• Bioconjugate Chemistry: Potential use in the development of labeled probes and diagnostic agents due to its reactive amino group.

Basic Information

Product Name	2(1H)-Pyrimidinone,4-Amino-5-Fluoro-6-(Fluoromethyl)-(9Ci)
CAS No.	606966-44-3
Molecular Formula	C5H5F2N3O
Molecular Weight	161.11 g/mol
Synonyms	4-Amino-5-fluoro-6-(fluoromethyl)pyrimidin-2(1H)-one; 4-Amino-5-fluoro-6-(fluoromethyl)-1,2-dihydropyrimidin-2-one; 4-Amino-5-fluoro-6-(fluoromethyl)-2(1H)-pyrimidinone; 5-Fluoro-6-(fluoromethyl)-4-aminopyrimidin-2(1H)-one; 606966-44-3; 4-Amino-5-fluoro-6-fluoromethyl-2-hydroxypyrimidine
EINECS	Contact for details

Quality Control

Our 2(1H)-Pyrimidinone,4-Amino-5-Fluoro-6-(Fluoromethyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.