Description

3H-1,2,3-Triazolo[4,5-D]Pyrimidine-5-Carboxamide, n-Cyclohexyl-3-[(4-Fluorophenyl)Methyl]-4,7-Dihydro-7-Oxo- (9Ci) is a high-value, complex heterocyclic organic compound with the CAS registry number 606135-03-9. This molecule serves as a critical advanced pharmaceutical intermediate (API) and a versatile scaffold in medicinal chemistry research. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Kinase Inhibitor Development: The triazolopyrimidine core is a privileged structure in the design of protein kinase inhibitors for oncology and inflammatory diseases.
• Biochemical Probe Synthesis: Utilized to create tool compounds for investigating biological mechanisms and target validation.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of specialized, non-commercial compounds for client research programs.
• Academic Research: Employed in university and institutional labs for cutting-edge organic synthesis and chemical biology projects.

Basic Information

Product Name	3H-1,2,3-Triazolo[4,5-D]Pyrimidine-5-Carboxamide, n-Cyclohexyl-3-[(4-Fluorophenyl)Methyl]-4,7-Dihydro-7-Oxo- (9Ci)
CAS No.	606135-03-9
Molecular Formula	C19H20FN7O2
Molecular Weight	397.41 g/mol
Synonyms	N-Cyclohexyl-3-[(4-fluorophenyl)methyl]-7-oxo-4,7-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-5-carboxamide; 3H-[1,2,3]Triazolo[4,5-d]pyrimidine-5-carboxamide, N-cyclohexyl-3-[(4-fluorophenyl)methyl]-4,7-dihydro-7-oxo-; CAS 606135-03-9; Triazolopyrimidine carboxamide derivative; Fluorophenylmethyl triazolopyrimidine; Advanced kinase inhibitor scaffold; Heterocyclic building block 606135-03-9.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and purified to meet exacting R&D and cGMP-grade standards, as required. Comprehensive analytical control includes HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. A detailed Certificate of Analysis (COA) with full chromatographic data and spectroscopic evidence is provided with each shipment to ensure complete traceability and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.