Description

Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-8-Methyl-4-Quinazolinyl]Thio]- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the research and development of novel therapeutic agents, particularly in kinase inhibitor programs. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Assay Development: Serves as a reference standard or probe compound in high-throughput screening (HTS) and enzymatic assays.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and novel synthetic pathways.
• Custom Synthesis: Basis for the contract manufacturing of proprietary drug candidates and specialized fine chemicals.

Basic Information

Product Name	Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-8-Methyl-4-Quinazolinyl]Thio]- (9Ci)
CAS No.	606132-87-0
Molecular Formula	C21H18FN3OS
Molecular Weight	379.45 g/mol
Synonyms	N-Cyclopropyl-2-((2-(4-fluorophenyl)-8-methylquinazolin-4-yl)thio)acetamide; 2-[[2-(4-Fluorophenyl)-8-methyl-4-quinazolinyl]thio]-N-cyclopropylacetamide; 606132-87-0; Acetamide, 2-[[2-(4-fluorophenyl)-8-methyl-4-quinazolinyl]thio]-N-cyclopropyl-; Quinazoline thioacetamide derivative
EINECS	Contact for details

Quality Control

Our production of Acetamide, n-Cyclopropyl-2-[[2-(4-Fluorophenyl)-8-Methyl-4-Quinazolinyl]Thio]- (9Ci) adheres to stringent quality protocols suitable for pharmaceutical R&D applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results from HPLC, NMR, and MS are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as argon or nitrogen in a sealed container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.