Description

Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid, 7-Hydroxy-2-(3-Methoxyphenyl)-, Ethyl Ester (9Ci) is a high-purity, synthetically valuable heterocyclic building block. This compound matters as a critical intermediate in the research and development of novel pharmaceutical agents, particularly in kinase inhibitor and anticancer drug discovery programs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for lead optimization and scalable synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of targeted small-molecule therapeutics, especially kinase inhibitors.
• Anticancer Drug Research: Used in the discovery and development of novel chemotherapeutic agents and targeted cancer therapies.
• Chemical Biology Probes: Serves as a core scaffold for creating tool compounds to study biological pathways and protein function.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies to improve drug potency and selectivity.
• Process Chemistry & Scale-Up: Utilized in route development and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the contract synthesis of complex, proprietary molecules for client-specific research programs.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid, 7-Hydroxy-2-(3-Methoxyphenyl)-, Ethyl Ester (9Ci)
CAS No.	606116-32-9
Molecular Formula	C₁₆H₁₅N₃O₄
Molecular Weight	313.31 g/mol
Synonyms	Ethyl 7-hydroxy-2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate; 7-Hydroxy-2-(3-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester; 606116-32-9; Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 7-hydroxy-2-(3-methoxyphenyl)-, ethyl ester; Ethyl 7-hydroxy-2-(m-anisyl)pyrazolo[1,5-a]pyrimidine-6-carboxylate
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-6-Carboxylic Acid, 7-Hydroxy-2-(3-Methoxyphenyl)-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure compliance with exacting research-grade and pharmaceutical intermediate standards. Comprehensive Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive compound.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.