Description

Pyrimidine, 2-[4-[1-(1-Cyclohexyl-1H-Tetrazol-5-Yl)Propyl]-1-Piperazinyl]- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of proprietary drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and safety profiles.
• Biochemical Tool Compound: Employed in in vitro assays to study enzyme inhibition or receptor binding mechanisms in pharmacological research.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized heterocyclic compounds.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and the development of new synthetic methodologies.

Basic Information

Product Name	Pyrimidine, 2-[4-[1-(1-Cyclohexyl-1H-Tetrazol-5-Yl)Propyl]-1-Piperazinyl]- (9Ci)
CAS No.	606114-25-4
Molecular Formula	C18H29N9
Molecular Weight	371.49 g/mol
Synonyms	2-[4-[1-(1-Cyclohexyl-1H-tetrazol-5-yl)propyl]-1-piperazinyl]pyrimidine; 2-(4-(1-(1-Cyclohexyl-1H-tetrazol-5-yl)propyl)piperazin-1-yl)pyrimidine; 606114-25-4; UNII-8KQ6IWH3VY; 8KQ6IWH3VY; SCHEMBL2180625; DTXSID60674469; AKOS005258209
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems to ensure batch-to-batch consistency and traceability. Each lot is analyzed using validated methods including HPLC, NMR, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development projects requiring compliance with ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.