Description

Thieno[2,3-D]Pyrimidin-4(1H)-One, 2-[[2-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)-2-Oxoethyl]Thio]-5,6-Dimethyl- (9Ci) is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidinone class of heterocyclic compounds. Its complex molecular architecture, featuring fused thiophene and pyrimidine rings, makes it a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on oncology, CNS disorders, and metabolic diseases.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new chemical entities.
• Biochemical Probe Development: Employed in the design and creation of chemical probes for investigating specific biological pathways and target validation in early-stage drug discovery.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-sponsored research programs.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis methodology and bioorganic chemistry.

Basic Information

Product Name	Thieno[2,3-D]Pyrimidin-4(1H)-One, 2-[[2-(2,3-Dihydro-1,4-Benzodioxin-6-Yl)-2-Oxoethyl]Thio]-5,6-Dimethyl- (9Ci)
CAS No.	606107-49-7
Molecular Formula	C₁₈H₁₆N₂O₃S₂
Molecular Weight	372.46 g/mol
Synonyms	2-[[2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]thio]-5,6-dimethylthieno[2,3-d]pyrimidin-4(1H)-one; 5,6-Dimethyl-2-({2-oxo-2-[2,3-dihydro-1,4-benzodioxin-6-yl]ethyl}thio)-1,4-dihydrothieno[2,3-d]pyrimidin-4-one; Thieno[2,3-d]pyrimidin-4(1H)-one, 2-[[2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-oxoethyl]thio]-5,6-dimethyl-; CAS 606107-49-7
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical starting materials, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.