Description

Pyrazolo[1,5-A]Pyrimidine-2-Carboxamide, 5-Cyclopropyl-n-(5-Methoxy-8-Quinolinyl)-7-(Trifluoromethyl)- (9Ci) is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a sophisticated heterocyclic scaffold for creating targeted therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing innovative drug candidates, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates in medicinal chemistry research.
• Oncology Research: Used in the development of targeted cancer therapies due to its specific molecular architecture.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent kinase inhibitors.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-up: Employed in route scouting and process optimization for API manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and pre-clinical development.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-2-Carboxamide, 5-Cyclopropyl-n-(5-Methoxy-8-Quinolinyl)-7-(Trifluoromethyl)- (9Ci)
CAS No.	606096-68-8
Molecular Formula	C₂₂H₁₈F₃N₅O₂
Molecular Weight	441.41 g/mol
Synonyms	5-Cyclopropyl-N-(5-methoxyquinolin-8-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide; 5-Cyclopropyl-7-(trifluoromethyl)-N-(5-methoxy-8-quinolinyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide; 5-Cyclopropyl-N-(5-methoxy-8-quinolinyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide; Pyrazolo[1,5-a]pyrimidine-2-carboxamide, 5-cyclopropyl-N-(5-methoxy-8-quinolinyl)-7-(trifluoromethyl)-; CAS 606096-68-8
EINECS	Contact for details

Quality Control

Our Pyrazolo[1,5-A]Pyrimidine-2-Carboxamide intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.