Description

Pyrazolo[1,5-A]Pyrimidine-2-Carboxamide, 5-(1-Methylethyl)-n-Tricyclo[3.3.1.13,7]Dec-1-Yl-7-(Trifluoromethyl)- (9Ci) is a sophisticated heterocyclic compound featuring a unique adamantane-derived substituent and a trifluoromethyl group, making it a valuable advanced intermediate for pharmaceutical research and development. Its complex, polycyclic structure is engineered to impart high metabolic stability and lipophilicity, which are critical for modulating biological targets in drug discovery programs. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

This specialized chemical intermediate serves critical functions in advanced synthetic chemistry, enabling the development of new molecular entities.

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, neurology, and antiviral research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its structural complexity for target specificity.
• Chemical Biology Probe: Serves as a core scaffold for creating molecular probes to study enzyme function and protein-protein interactions.
• Material Science Research: Investigated as a precursor for advanced organic electronic materials due to its rigid, three-dimensional structure.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-2-Carboxamide, 5-(1-Methylethyl)-n-Tricyclo[3.3.1.13,7]Dec-1-Yl-7-(Trifluoromethyl)- (9Ci)
CAS No.	606096-61-1
Molecular Formula	C21H25F3N4O
Molecular Weight	406.45 g/mol
Synonyms	5-Isopropyl-N-(1-adamantyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide; 5-(1-Methylethyl)-N-tricyclo[3.3.1.13,7]dec-1-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide; Adamantyl pyrazolopyrimidine carboxamide derivative; 606096-61-1; 5-Isopropyl-N-adamantan-1-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data to support your research and regulatory needs. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to prevent decomposition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.