Description

5-Nitropyridine-3-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic building block in advanced organic synthesis. Its core value lies in its ability to introduce the 5-nitro-3-sulfonyl moiety, a crucial functional group for constructing complex molecules with specific electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonyl group enhances biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the creation of functional polymers and advanced organic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and labeling of biomolecules due to its electrophilic sulfonyl chloride group.
• Dye & Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments containing nitro and sulfonyl functional groups.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and scale-up projects.

Basic Information

Product Name	5-Nitropyridine-3-Sulfonyl Chloride
CAS No.	605653-17-6
Molecular Formula	C5H3ClN2O4S
Molecular Weight	222.61 g/mol
Synonyms	3-Pyridinesulfonyl chloride, 5-nitro-; 5-Nitro-3-pyridinesulfonyl chloride; 5-Nitropyridine-3-sulfonyl chloride; 605653-17-6; 3-Chlorosulfonyl-5-nitropyridine; 5-Nitro-pyridine-3-sulfonyl chloride; 5-Nitro-3-sulfonylchloropyridine
EINECS	Contact for details

Quality Control

Our 5-Nitropyridine-3-Sulfonyl Chloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.