Description

3-Piperidinecarboxamide,n-2-Propynyl-1-(2-Pyrimidinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate of significant interest in modern medicinal chemistry. This compound matters for its role as a critical building block in the research and development of novel therapeutic agents, particularly those targeting the central nervous system. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for synthesizing potential drug candidates, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Neurological & Psychiatric Drug Development: A valuable scaffold for compounds targeting receptors and enzymes within the central nervous system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic methodologies and biological mechanisms.
• Pre-clinical Studies: Employed in the synthesis of compounds for pharmacological profiling and toxicology assessments.

Basic Information

Product Name	3-Piperidinecarboxamide,n-2-Propynyl-1-(2-Pyrimidinyl)-(9Ci)
CAS No.	605624-33-7
Molecular Formula	C13H16N4O
Molecular Weight	244.29 g/mol
Synonyms	N-Prop-2-yn-1-yl-1-(pyrimidin-2-yl)piperidine-3-carboxamide; 1-(2-Pyrimidinyl)-N-(2-propynyl)-3-piperidinecarboxamide; 3-Piperidinecarboxamide, 1-(2-pyrimidinyl)-N-2-propynyl-; UNII-8J8F8K4R6F; 8J8F8K4R6F; 1-(Pyrimidin-2-yl)-N-(prop-2-yn-1-yl)piperidine-3-carboxamide; AOB677; 1-(2-Pyrimidinyl)-N-(2-propynyl)-3-piperidinecarboxamide (9CI)
EINECS	Contact for details

Quality Control

Our 3-Piperidinecarboxamide,n-2-Propynyl-1-(2-Pyrimidinyl)-(9Ci) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, meeting the stringent requirements for pharmaceutical R&D. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable to support our clients' regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.