Description

Piperazine, 1-(4-Fluorophenyl)-4-[[1-(2-Pyrimidinyl)-3-Piperidinyl]Carbonyl]- (9Ci) is a sophisticated piperazine-based organic building block with a complex heterocyclic structure. This compound matters as a key advanced intermediate in modern pharmaceutical research and development, enabling the synthesis of novel therapeutic agents. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the creation of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probe Development: Serves as a scaffold for creating molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, complex heterocyclic intermediates.

Basic Information

Product Name	Piperazine, 1-(4-Fluorophenyl)-4-[[1-(2-Pyrimidinyl)-3-Piperidinyl]Carbonyl]- (9Ci)
CAS No.	605624-02-0
Molecular Formula	C26H28FN5O
Molecular Weight	445.54 g/mol
Synonyms	1-(4-Fluorophenyl)-4-[[1-(2-pyrimidinyl)-3-piperidinyl]carbonyl]piperazine; 4-[(1-Pyrimidin-2-ylpiperidin-3-yl)carbonyl]-1-(4-fluorophenyl)piperazine; 1-(4-Fluorophenyl)-4-[(1-pyrimidin-2-ylpiperidin-3-yl)carbonyl]piperazine; 605624-02-0; UNII-9K3R4JZ0QN; 9K3R4JZ0QN; SCHEMBL218422; AOB67707; BDBM50388879; AKOS025310924; AS-81033; ZINC000003869756
EINECS	Contact for details

Quality Control

Our high-value chemical intermediates are produced under strict quality management systems. Each batch of Piperazine, 1-(4-Fluorophenyl)-4-[[1-(2-Pyrimidinyl)-3-Piperidinyl]Carbonyl]- (9Ci) undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.