Description

Piperazine, 1-Acetyl-4-[3-(4-Chlorophenyl)Isothiazolo[4,5-D]Pyrimidin-7-Yl]- (9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and targeted drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring a reliable and consistent supply of high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the development and preclinical study of new anticancer drug candidates due to its specific molecular scaffold.
• Biochemical Research: Employed as a reference standard or a probe compound in biochemical assays to study enzyme inhibition and cellular signaling pathways.
• Fine Chemical Synthesis: Acts as a versatile precursor for the preparation of more complex, functionalized isothiazolopyrimidine derivatives.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Piperazine, 1-Acetyl-4-[3-(4-Chlorophenyl)Isothiazolo[4,5-D]Pyrimidin-7-Yl]- (9Ci)
CAS No.	604741-49-3
Molecular Formula	C17H14ClN5OS
Molecular Weight	371.84 g/mol
Synonyms	1-Acetyl-4-[3-(4-chlorophenyl)isothiazolo[4,5-d]pyrimidin-7-yl]piperazine; 7-[4-(Acetyl)piperazin-1-yl]-3-(4-chlorophenyl)isothiazolo[4,5-d]pyrimidine; 3-(4-Chlorophenyl)-7-(4-acetylpiperazin-1-yl)isothiazolo[4,5-d]pyrimidine; 604741-49-3; UNII-9I6V8Y4R2T; 9I6V8Y4R2T; AKOS025310991; AS-64165; BDBM50389305; SY054625; ZINC000003869756
EINECS	Contact for details

Quality Control

Our production of Piperazine, 1-Acetyl-4-[3-(4-Chlorophenyl)Isothiazolo[4,5-D]Pyrimidin-7-Yl]- (9Ci) adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.