Description

Piperazine, 1-[3-(4-Fluorophenyl)Isothiazolo[4,5-D]Pyrimidin-7-Yl]-4-(1-Oxobutyl)- (9Ci) is a sophisticated heterocyclic organic compound designed for advanced chemical synthesis and pharmaceutical research. This molecule matters as a high-value pharmaceutical intermediate or active pharmaceutical ingredient (API) building block, offering a unique structural framework for developing novel therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly those focused on kinase inhibitors or other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially those targeting specific enzymes or cellular pathways.
• Kinase Inhibitor Research: The fused isothiazolopyrimidine core structure is indicative of applications in the development of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry & SAR Studies: Used by research laboratories to explore structure-activity relationships (SAR) and optimize the potency and selectivity of lead compounds.
• Process Chemistry & Scale-Up: Employed in process development for optimizing synthetic routes and scaling up the production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: May be utilized as a reference standard or probe molecule in biochemical and cellular assays to study biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs (Contract Development and Manufacturing Organizations) for the custom synthesis of client-specific molecules.

Basic Information

Item	Details
Product Name	Piperazine, 1-[3-(4-Fluorophenyl)Isothiazolo[4,5-D]Pyrimidin-7-Yl]-4-(1-Oxobutyl)- (9Ci)
CAS No.	604741-36-8
Molecular Formula	C19H18FN5OS
Molecular Weight	383.44 g/mol
Synonyms	1-[3-(4-Fluorophenyl)isothiazolo[4,5-d]pyrimidin-7-yl]-4-butanoylpiperazine; 4-Butanoyl-1-[3-(4-fluorophenyl)[1,2]thiazolo[4,5-d]pyrimidin-7-yl]piperazine; 1-(3-(4-Fluorophenyl)isothiazolo[4,5-d]pyrimidin-7-yl)-4-butanoylpiperazine; 604741-36-8; Butanoylpiperazine derivative; Fluorophenyl-isothiazolopyrimidine-piperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 1-[3-(4-Fluorophenyl)Isothiazolo[4,5-D]Pyrimidin-7-Yl]-4-(1-Oxobutyl)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques such as HPLC, NMR, and MS to confirm identity and purity, ensuring it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.