Description

Propanoic Acid, 2-[(8-Fluoro-2H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]-, Ethyl Ester (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating fluorine and sulfur. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting specific therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing next-generation drugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new drug candidates, especially those with indole and triazine pharmacophores.
• Anticancer Agent Research: Used in the synthesis of potential anticancer compounds due to the biological activity associated with its fused indole-triazine core structure.
• Kinase Inhibitor Development: Applied in medicinal chemistry programs focused on creating selective kinase inhibitors for targeted therapies.
• Chemical Biology Probes: Utilized as a scaffold or precursor for developing molecular probes to study biological pathways and protein functions.
• Process Chemistry & Scale-Up: Employed in process optimization and pilot-scale synthesis for potential commercial pharmaceutical manufacturing.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	Propanoic Acid, 2-[(8-Fluoro-2H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]-, Ethyl Ester (9Ci)
CAS No.	603947-93-9
Molecular Formula	C14H11FN4O2S
Molecular Weight	318.33 g/mol
Synonyms	Ethyl 2-[(8-Fluoro-2H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]propanoate; 2-[(8-Fluoro-2H-1,2,4-triazino[5,6-b]indol-3-yl)thio]propanoic Acid Ethyl Ester; 603947-93-9; 8-Fluoro-3-[(1-ethoxycarbonyl)ethylthio]-2H-[1,2,4]triazino[5,6-b]indole; Propanoic acid, 2-[(8-fluoro-2H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-[(8-Fluoro-2H-1,2,4-Triazino[5,6-B]Indol-3-Yl)Thio]-, Ethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material at temperatures between 2°C and 8°C. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.