Description

β-Endorphin (1-18) is a bioactive peptide fragment derived from the endogenous opioid peptide β-endorphin. This compound is of significant interest for its role in neurobiological research and its potential as a reference standard in analytical and pharmacological studies. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focusing on pain pathways, stress response, and neuroendocrine function.

Application

• Neuroscience Research: Used as a tool compound to study opioid receptor binding, signal transduction, and the physiological effects of endorphins.
• Biochemical Assay Development: Serves as a critical reference standard or antigen in the development of immunoassays (ELISA, RIA) for β-endorphin detection.
• Pharmacological Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate novel analgesic or neuroactive compounds.
• Academic & Clinical Studies: Facilitates research into stress, pain modulation, addiction mechanisms, and mental health disorders.
• Peptide Chemistry & Synthesis: Acts as a building block or intermediate for the synthesis of longer peptide chains or modified analogs.
• Quality Control & Validation: Used as a system suitability standard in analytical methods (e.g., HPLC, LC-MS) for peptide purity and identity confirmation.

Basic Information

Item	Detail
Product Name	β-Endorphin (1-18)
CAS No.	69977-04-4
Molecular Formula	C98H140N24O27S
Molecular Weight	2166.4 g/mol
Synonyms	β-Endorphin (1-18); β-Endorphin 1-18; Endorphin, β- (1-18); Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-OH; β-Lipotropin (61-78); LPH (61-78)
EINECS	Contact for details

Quality Control

Our β-Endorphin (1-18) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Conforms to theoretical values (±10%)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.