Description

n-α-Acetylarginine-Ethylamide is a chemically modified derivative of the amino acid arginine, featuring acetylation at the α-amino group and ethylamide at the carboxyl terminus. This specific modification enhances its stability and bioavailability, making it a valuable building block in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of peptide synthesis, medicinal chemistry, and as a reference standard for analytical purposes.

Application

• Peptide Synthesis Intermediate: A key protected amino acid derivative for the solid-phase and solution-phase synthesis of novel peptides and peptidomimetics.
• Medicinal Chemistry Research: Serves as a crucial precursor or scaffold in the development of new therapeutic agents targeting various biological pathways.
• Biochemical Reference Standard: Used for method development, calibration, and quality control in analytical laboratories employing HPLC, LC-MS, or NMR.
• Enzyme Substrate/Analogue: Investigated in studies related to arginine-metabolizing enzymes, such as nitric oxide synthases or arginases.
• Cosmetic & Dermatological Actives: Explored for potential use in high-end skincare formulations due to arginine's role in skin barrier function and hydration.

Basic Information

Item	Detail
Product Name	n-α-Acetylarginine-Ethylamide
CAS No.	69976-90-5
Molecular Formula	C10H21N5O3
Molecular Weight	259.31 g/mol
Synonyms	N-α-Acetyl-L-arginine ethylamide; Ac-Arg-NHEt; L-Arginine, N2-acetyl-, ethylamide; N-Acetylarginine ethylamide; Acetyl arginine ethyl ester amide; Ethyl 2-acetamido-5-guanidinopentanoate; 69976-90-5; Nalpha-Acetyl-L-arginine ethylamide
EINECS	Contact for details

Quality Control

Our n-α-Acetylarginine-Ethylamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]20/D: Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.