Description

2,4-Diamino-5-(3-Fluorobenzyl)Pyrimidine is a high-purity, specialized pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and fluorobenzyl substituents, makes it a valuable intermediate for creating compounds with targeted biological activity. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of dihydrofolate reductase (DHFR) inhibitors and other potential therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its pyrimidine core for bioactivity.
• Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in medicinal chemistry programs.
• Biochemical Research: Employed in studies investigating enzyme inhibition and structure-activity relationships (SAR).
• Material Science: Potential intermediate for the synthesis of specialty chemicals and functional materials.

Basic Information

Product Name	2,4-Diamino-5-(3-Fluorobenzyl)Pyrimidine
CAS No.	69945-57-9
Molecular Formula	C11H11FN4
Molecular Weight	218.23 g/mol
Synonyms	5-(3-Fluorobenzyl)-2,4-pyrimidinediamine; 3-Fluorobenzylpyrimidine-2,4-diamine; 2,4-Diamino-5-(3-fluorobenzyl)pyrimidine; 5-(3-Fluorobenzyl)-2,4-diaminopyrimidine; 2,4-Pyrimidinediamine, 5-[(3-fluorophenyl)methyl]-; 69945-57-9
EINECS	Contact for details

Quality Control

Our 2,4-Diamino-5-(3-Fluorobenzyl)Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.