Description

2,4-Diamino-5-(4-Nitrobenzyl)Pyrimidine is a high-purity pyrimidine derivative, a crucial organic intermediate in advanced chemical synthesis. Its value lies in its functionalized structure, which serves as a versatile building block for creating complex molecules with specific biological or material properties. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of dihydrofolate reductase (DHFR) inhibitors and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides and fungicides, leveraging its pyrimidine core.
• Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds and fine chemicals.
• Biochemical Research: Employed in studies involving enzyme inhibition and as a substrate analog in biochemical assays.
• Material Science: Potential intermediate for the synthesis of organic electronic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	2,4-Diamino-5-(4-Nitrobenzyl)Pyrimidine
CAS No.	69945-52-4
Molecular Formula	C11H11N5O2
Molecular Weight	245.24 g/mol
Synonyms	5-[(4-Nitrophenyl)methyl]-2,4-pyrimidinediamine; 5-(4-Nitrobenzyl)-2,4-diaminopyrimidine; 2,4-Diamino-5-(p-nitrobenzyl)pyrimidine; 2,4-Pyrimidinediamine, 5-[(4-nitrophenyl)methyl]-; 5-(4-Nitrobenzyl)pyrimidine-2,4-diamine; NSC 329680; 4-Nitrobenzylpyrimidine derivative
EINECS	Contact for details

Quality Control

Our 2,4-Diamino-5-(4-Nitrobenzyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.