Description

Vip (10-28) (Human, Bovine, Porcine, Rat) is a bioactive peptide fragment derived from Vasoactive Intestinal Polypeptide. This compound is a critical research tool for studying neuroendocrine signaling, immune modulation, and cardiovascular function across multiple species. It is essential for pharmaceutical R&D, academic research, and diagnostic development in the life sciences. The product is supplied as a high-purity, lyophilized powder suitable for in vitro and in vivo studies.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies of VIP receptor (VPAC1, VPAC2) binding, activation, and downstream signaling pathways.
• Neurobiology Studies: Investigation of VIP's role as a neuromodulator and neurotransmitter in the central and peripheral nervous systems.
• Immunology Assays: Research into the immunomodulatory effects of VIP on cytokine production, T-cell differentiation, and inflammatory responses.
• Cardiovascular Research: Study of vasodilation, smooth muscle relaxation, and cardiac function regulation.
• Endocrinology: Exploration of interactions with other hormonal systems and metabolic processes.
• Diagnostic Development: Serves as a critical antigen for the production and calibration of immunoassays and antibodies targeting VIP.
• Cross-Species Comparative Studies: Enables comparative analysis of VIP structure and function in human, bovine, porcine, and rat models.

Basic Information

Product Name	Vip (10-28) (Human, Bovine, Porcine, Rat)
CAS No.	69856-17-3
Molecular Formula	C98H153N29O26S
Molecular Weight	~2240.5 g/mol
Synonyms	VIP (10-28); Vasoactive Intestinal Peptide (10-28); VIP Fragment 10-28; Human VIP (10-28); Porcine VIP (10-28); Bovine VIP (10-28); Rat VIP (10-28); Vasoactive Intestinal Polypeptide (10-28); [Tyr10]-VIP (10-28) (human); VPAC Receptor Ligand Fragment
EINECS	Contact for details

Quality Control

Our Vip (10-28) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data on purity (typically >95%), peptide content, water content (by KF), and endotoxin levels. Our quality commitment ensures reproducible performance and reliable results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Composition	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.