Description

5-Fluoro-1-(2-Propyn-1-Yl)-2,4(1H,3H)-Pyrimidinedione is a specialized fluorinated pyrimidinedione derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular scaffold, which enables the introduction of both fluorine and a propargyl functional group into target molecules, a key strategy in modern medicinal and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and life sciences sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the biological activity of fluorinated heterocycles.
• Chemical Biology Probe: The propargyl group allows for "click chemistry" applications, enabling the study of biological pathways and target identification.
• Organic Synthesis Building Block: Employed in academic and industrial research to construct complex heterocyclic systems for material science and catalysis.

Basic Information

Product Name	5-Fluoro-1-(2-Propyn-1-Yl)-2,4(1H,3H)-Pyrimidinedione
CAS No.	69849-33-8
Molecular Formula	C7H5FN2O2
Molecular Weight	168.13 g/mol
Synonyms	5-Fluoro-1-propargyluracil; 5-Fluoro-1-(prop-2-yn-1-yl)pyrimidine-2,4(1H,3H)-dione; 1-Propargyl-5-fluorouracil; 5-Fluoro-1-(2-propynyl)uracil; 5-Fluoro-1-(prop-2-ynyl)uracil; 5-Fluorouracil, 1-propargyl-; 69849-33-8
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-(2-Propyn-1-Yl)-2,4(1H,3H)-Pyrimidinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.