Description

2(1H)-Pyrimidinone, 5-(Hydroxymethyl)- (9Ci) is a heterocyclic organic compound featuring a pyrimidinone core with a hydroxymethyl substituent. This functionalized pyrimidine derivative serves as a versatile and valuable building block in advanced organic synthesis, particularly for the development of nucleoside analogs and other bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of modified nucleosides and nucleotides with potential antiviral or anticancer activity.
• Agrochemical Research: Used in the development of new herbicides and fungicides that target specific biochemical pathways in plants and pests.
• Biochemical Probe Synthesis: Employed to create labeled or modified compounds for studying enzymatic mechanisms and biological interactions.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex chelating agents or organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional unit for creating novel polymers with specific electronic or photonic properties.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental research in medicinal and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	2(1H)-Pyrimidinone, 5-(Hydroxymethyl)- (9Ci)
CAS No.	69849-31-6
Molecular Formula	C5H6N2O2
Molecular Weight	126.11 g/mol
Synonyms	5-(Hydroxymethyl)-2(1H)-pyrimidinone; 5-(Hydroxymethyl)uracil; 5-Hydroxymethyluracil; 5-HMU; 5-Hydroxymethyl-2-pyrimidinol; 5-(Hydroxymethyl)-1H-pyrimidin-2-one; 5-(Hydroxymethyl)pyrimidine-2,4(1H,3H)-dione (tautomer); Isodialuric acid 5-hydroxymethyl derivative
EINECS	Contact for details

Quality Control

Our production of 2(1H)-Pyrimidinone, 5-(Hydroxymethyl)- adheres to a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.