Description

7-Fluoro-2-Mercaptoquinazolin-4(3H)-One is a high-purity fluorinated quinazolinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for synthesizing novel bioactive compounds targeting specific therapeutic pathways. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in developing novel herbicides and fungicides, leveraging the bioactivity of the quinazolinone core.
• Chemical Biology Probe: Serves as a precursor for fluorescent tags or activity-based probes in biochemical research.
• Material Science: Potential monomer or additive in the development of specialty polymers with specific optical or electronic properties.
• Academic & Contract Research: Fundamental reagent for organic synthesis and medicinal chemistry projects in university and CRO laboratories.

Basic Information

Item	Details
Product Name	7-Fluoro-2-Mercaptoquinazolin-4(3H)-One
CAS No.	69661-43-4
Molecular Formula	C8H5FN2OS
Molecular Weight	196.20 g/mol
Synonyms	7-Fluoro-4-hydroxy-2-mercaptoquinazoline; 7-Fluoro-2-thioxo-1,2-dihydroquinazolin-4(3H)-one; 7-Fluoro-2-mercapto-3H-quinazolin-4-one; 2-Mercapto-7-fluoroquinazolin-4(3H)-one; 69661-43-4; 7-Fluoro-2-thioxo-2,3-dihydroquinazolin-4(1H)-one; 7-Fluoro-2-sulfanyl-3H-quinazolin-4-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-2-Mercaptoquinazolin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store the material under an inert atmosphere for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.