Description

Glucagon (1-6) is a synthetic hexapeptide fragment of the glucagon hormone, specifically comprising the first six amino acids from the N-terminus. This peptide sequence is of significant interest in biochemical and pharmaceutical research for studying glucagon receptor interactions and metabolic pathways. It serves as a critical intermediate and reference standard for scientists and manufacturers in the fields of endocrinology, peptide synthesis, and drug discovery.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying the structure-activity relationship (SAR) of glucagon and its receptor binding.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel glucagon analogs and peptide-based therapeutics targeting metabolic disorders.
• Diagnostic Reagent Manufacturing: Employed in the development and calibration of immunoassays and diagnostic kits for glucagon-related studies.
• Academic & Institutional Laboratories: Utilized in university and research institute settings for fundamental studies on peptide hormones, diabetes, and liver metabolism.
• Peptide Library Synthesis: Acts as a building block or a template in combinatorial chemistry for creating focused libraries of bioactive peptides.

Basic Information

Product Name	Glucagon (1-6)
CAS No.	69658-84-0
Molecular Formula	C30H46N10O9
Molecular Weight	690.8 g/mol
Synonyms	Glucagon Fragment 1-6; H-His-Ser-Gln-Gly-Thr-Phe-OH; HGQGTF; Glucagon (1-6) amide (precursor); Glucagon hexapeptide; Glucagon N-terminal hexapeptide; Glucagon(1-6) peptide
EINECS	Contact for details

Quality Control

Our Glucagon (1-6) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, identity, and other critical parameters is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ±10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.