Description

L-Glutamic Acid, 5-(2-(4-Carboxyphenyl)Hydrazide) is a specialized derivative of glutamic acid, featuring a hydrazide linkage to a carboxyphenyl group. This unique bifunctional structure makes it a valuable intermediate and building block for the synthesis of more complex molecules in advanced research and development. It is primarily sought by industries focused on pharmaceutical development, biochemical research, and fine chemical synthesis, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and diagnostic agents.
• Bioconjugation & Linker Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and protein modification due to its reactive hydrazide and carboxylic acid groups.
• Biochemical Research: Acts as a specialized reagent or substrate in enzymatic studies and metabolic pathway investigations.
• Peptide Mimetic Synthesis: Employed as a non-natural amino acid analog for creating peptide-like compounds with enhanced stability or specific binding properties.
• Chelating Agent Precursor: Used in the development of ligands for metal chelation in catalytic or analytical applications.
• Material Science Research: Investigated as a monomer or cross-linking agent for the creation of functional polymers and hydrogels.

Basic Information

Product Name	L-Glutamic Acid, 5-(2-(4-Carboxyphenyl)Hydrazide)
CAS No.	69644-85-5
Molecular Formula	C12H13N3O5
Molecular Weight	279.25 g/mol
Synonyms	5-(2-(4-Carboxyphenyl)hydrazinyl)-5-oxopentanoic acid; L-Glutamic acid N'-(4-carboxybenzoyl)hydrazide; N-(4-Carboxybenzoyl)-L-glutamic acid hydrazide; (2S)-2-Amino-5-[[(4-carboxyphenyl)carbonyl]amino]pentanoic acid; Glutamic acid, 5-[(4-carboxybenzoyl)hydrazide]; L-Glutamic acid γ-(4-carboxybenzhydrazide); 4-Carboxybenzoic acid L-glutamylhydrazone
EINECS	Contact for details

Quality Control

Our L-Glutamic Acid, 5-(2-(4-Carboxyphenyl)Hydrazide) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, chiral purity, and impurity profiles. We support cGMP compliance for relevant applications, and specifications can be aligned with client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% L-Isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.