Description

2-Amino-5-[[[(1S,4S,5R)-4,5-Dihydroxycyclopent-2-En-1-Yl]Amino]Methyl]-1,7-Dihydropyrrolo[2,3-D]Pyrimidin-4-One is a sophisticated, high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for the creation of novel antiviral and anticancer agents, particularly those targeting viral polymerases and cellular signaling pathways. Pharmaceutical companies, biotechnology research firms, and advanced academic laboratories engaged in nucleoside chemistry and medicinal chemistry need this precise chemical for developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral drugs, including potential treatments for viral infections.
• Anticancer Agent Research: Used in the development and study of experimental chemotherapeutic compounds that interfere with DNA/RNA synthesis in cancer cells.
• Medicinal Chemistry & Drug Discovery: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the optimization of biological activity in lead compounds.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and polymerases.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	2-Amino-5-[[[(1S,4S,5R)-4,5-Dihydroxycyclopent-2-En-1-Yl]Amino]Methyl]-1,7-Dihydropyrrolo[2,3-D]Pyrimidin-4-One
CAS No.	69565-92-0
Molecular Formula	C₁₃H₁₅N₅O₃
Molecular Weight	289.29 g/mol
Synonyms	Carbocyclic Nucleoside Analog Intermediate; (1S,4S,5R)-4,5-Dihydroxy-2-cyclopenten-1-amine Derivative; 4-Amino-7H-pyrrolo[2,3-d]pyrimidine Derivative; 2-Amino-5-(((1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl)aminomethyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one; Cyclopentenyl Pyrrolopyrimidinone; Nucleoside Mimetic Building Block; CAS 69565-92-0
EINECS	Contact for details

Quality Control

Our 2-Amino-5-[[[(1S,4S,5R)-4,5-Dihydroxycyclopent-2-En-1-Yl]Amino]Methyl]-1,7-Dihydropyrrolo[2,3-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) documenting full specifications are available for every lot to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and may be hygroscopic; therefore, it should be handled under an inert atmosphere when appropriate and kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.