Description

4-Bromo-6-Methoxypyrimidine is a versatile halogenated pyrimidine derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the reactive bromine atom and methoxy group, which enable precise functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging the pyrimidine core's bioactivity.
• Material Science Precursor: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Cross-Coupling Reactions: Serves as a reliable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form new carbon-carbon bonds.
• Nucleoside & Nucleobase Chemistry: Acts as a precursor for modified nucleosides and heterocyclic compounds used in biochemical research and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	4-Bromo-6-Methoxypyrimidine
CAS No.	69543-97-1
Molecular Formula	C5H5BrN2O
Molecular Weight	189.01 g/mol
Synonyms	6-Methoxy-4-bromopyrimidine; 4-Bromo-6-methoxy-1,3-diazine; 4-Bromo-6-methoxypyrimidine; 4-Bromo-6-pyrimidinol, methyl ether; 69543-97-1; NSC 403119
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6-Methoxypyrimidine is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques, including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.