Description

2,4-Pyrimidinediamine, 5-((3,4,5-Trimethoxyphenyl)Methyl)-, Monohydrat E is a specialized pyrimidine derivative of significant interest in advanced organic synthesis. This compound matters as a critical building block for developing novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a unique molecular scaffold. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and life science sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential therapeutic agents, particularly in oncology and antiviral research.
• Biochemical Research: Used as a reference standard or building block in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Development: Acts as a starting material for creating novel crop protection agents and pesticides.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of complex, high-value specialty chemicals.
• Academic & Industrial R&D: Utilized in laboratories for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2,4-Pyrimidinediamine, 5-((3,4,5-Trimethoxyphenyl)Methyl)-, Monohydrat E
CAS No.	69449-07-6
Molecular Formula	C14H20N4O4 • H2O
Molecular Weight	320.34 g/mol (Monohydrate)
Synonyms	5-((3,4,5-Trimethoxyphenyl)methyl)pyrimidine-2,4-diamine monohydrate; 5-(3,4,5-Trimethoxybenzyl)-2,4-pyrimidinediamine monohydrate; 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine monohydrate; Trimethoprim Impurity; Trimethoprim Related Compound; NSC 339586; 69449-07-6 (Monohydrate)
EINECS	Contact for details

Quality Control

Our 2,4-Pyrimidinediamine, 5-((3,4,5-Trimethoxyphenyl)Methyl)-, Monohydrat E is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and other relevant techniques are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.5% - 6.5% (Theoretical for monohydrate: ~5.6%)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.