Description

Somatostatin, Val(1)-Trp(8)- is a synthetic analogue of the endogenous peptide hormone somatostatin, characterized by specific amino acid substitutions at positions 1 and 8. This modification can enhance its stability and receptor-binding profile, making it a valuable tool for advanced biochemical and pharmacological research. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on endocrinology, neurobiology, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of somatostatin receptor (SSTR) signaling pathways and hormone regulation.
• Pharmacological Development: Serves as a key intermediate or lead compound in the design and screening of new peptide-based therapeutics targeting metabolic disorders or cancers.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays (e.g., ELISA, RIA) for detecting somatostatin or related biomarkers.
• Cell Culture & Physiology Studies: Applied in cell-based assays to investigate the inhibitory effects on growth hormone, insulin, or glucagon secretion.
• Neuroscience Research: Utilized to study the role of somatostatin as a neurotransmitter or neuromodulator in the central and peripheral nervous systems.

Basic Information

Product Name	Somatostatin, Val(1)-Trp(8)-
CAS No.	69405-26-1
Molecular Formula	C76H104N18O19S2
Molecular Weight	1637.9 g/mol
Synonyms	Val1,Trp8-Somatostatin-14; [Val1,Trp8]-Somatostatin; Somatostatin (1-14), Val1-Trp8-; H-Val-Ala-Gly-Cys-Lys-Asn-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (disulfide bridge: Cys3-Cys14); SRIF analogue; Growth hormone release-inhibiting factor analogue
EINECS	Contact for details

Quality Control

Our Somatostatin, Val(1)-Trp(8)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.