Description

n-(3-Amino-2-Hydroxy-5-Methylhexanoyl)-L-Val-L-Val-L-Asp-Oh is a synthetic tetrapeptide derivative, specifically designed for advanced research and development applications. This compound is valued for its role as a key intermediate or building block in the synthesis of more complex bioactive peptides and peptidomimetics. It is primarily utilized by pharmaceutical R&D teams, biotechnology firms, and academic research institutions focused on drug discovery, particularly in areas involving enzyme inhibitors or novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and proteomics research to investigate biological pathways.
• Peptidomimetic Development: Acts as a core structure for designing and synthesizing peptidomimetics with enhanced stability and bioavailability.
• Protease Inhibitor Synthesis: A key precursor in the development of specific protease inhibitors for therapeutic applications.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploratory chemistry.
• Custom Peptide Synthesis: Used by specialized manufacturers for the custom production of complex peptide sequences for clients.

Basic Information

Item	Detail
Product Name	n-(3-Amino-2-Hydroxy-5-Methylhexanoyl)-L-Val-L-Val-L-Asp-Oh
CAS No.	69400-55-1
Molecular Formula	C22H40N4O7
Molecular Weight	472.58 g/mol
Synonyms	AHMHA-Val-Val-Asp-OH; (2S)-2-[(2S)-2-[(2S)-2-[[(2S,3R)-3-Amino-2-hydroxy-5-methylhexanoyl]amino]-3-methylbutanamido]-3-methylbutanamido]butanedioic acid; Tetrapeptide AHMHA-Val-Val-Asp; L-Val-L-Val-L-Asp derivative; n-(3-Amino-2-hydroxy-5-methylhexanoyl)valylvalylaspartic acid; Peptide building block 69400-55-1; AHMHA-containing peptide
EINECS	Contact for details

Quality Control

Our n-(3-Amino-2-Hydroxy-5-Methylhexanoyl)-L-Val-L-Val-L-Asp-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and NMR. We provide a Certificate of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures material suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.