Description

Berberine Sulfate Trihydrate is a high-purity, crystalline alkaloid salt derived from natural sources. This compound is valued for its potent biological activity and serves as a critical reference standard and active ingredient in advanced research and manufacturing. It is essential for industries focused on developing nutraceutical, pharmaceutical, and high-grade research applications where consistent quality and precise chemical identity are paramount.

Application

• As a primary reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Key active pharmaceutical ingredient (API) in the formulation of dietary supplements and nutraceuticals targeting metabolic health.
• Critical raw material for preclinical and clinical research studies investigating metabolic pathways and bioactive compounds.
• Intermediate in the synthesis of more complex berberine derivatives for specialized pharmaceutical applications.
• Used in the production of high-purity reagents for biochemical and microbiological research.
• Ingredient in the development of functional ingredients for the food and beverage industry, subject to regulatory approval.

Basic Information

Product Name	Berberine Sulfate Trihydrate
CAS No.	69352-97-2
Molecular Formula	C20H18NO4 · H2SO4 · 3H2O
Molecular Weight	564.57 g/mol
Synonyms	Berberine Sulfate; Berberine Sulphate; Berberine Hydrogen Sulfate; Berberine Bisulfate; Natural Yellow 18 Sulfate; Umbellatine Sulfate; 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Sulfate Trihydrate
EINECS	Contact for details

Quality Control

Our Berberine Sulfate Trihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for research and development purposes. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	8.0% - 10.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.