Description

(E)-5-(2-Bromovinyl)Uracil is a halogenated pyrimidine nucleoside analog with significant research and synthetic utility. This compound is valued for its role as a key intermediate in the development of antiviral and anticancer agents, particularly those targeting viral polymerases. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in nucleoside chemistry and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel antiviral nucleoside analogs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop treatments for viral infections.
• Biochemical Probe: Serves as a substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and repair.
• Organic Synthesis: Acts as a versatile intermediate for introducing modified uracil moieties into more complex molecular architectures.
• Antiviral Agent Development: Investigated for its potential activity and as a precursor in the synthesis of compounds targeting herpesviruses and other DNA viruses.

Basic Information

Product Name	(E)-5-(2-Bromovinyl)Uracil
CAS No.	69304-49-0
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	5-[(E)-2-Bromoethenyl]uracil; (E)-5-(2-Bromovinyl)-2,4(1H,3H)-pyrimidinedione; BVDU; Brivudin Impurity; (E)-5-(2-Bromovinyl)Uracyl; 2,4(1H,3H)-Pyrimidinedione, 5-[(E)-2-bromoethenyl]-; 5-(2-Bromovinyl)uracil (E-isomer); NSC 38292
EINECS	Contact for details

Quality Control

Our (E)-5-(2-Bromovinyl)Uracil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.