Description

4H-Pyrimido[2,1-A]Isoquinoline-3-Carboxylic Acid, 6,7-Dihydro-10-(2-Methyl-1-Oxopropoxy)-4-Oxo- is a high-purity, complex heterocyclic carboxylic acid derivative with significant synthetic utility. This compound serves as a critical advanced pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical R&D departments engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Organic Synthesis Research: Used as a sophisticated precursor for constructing fused polycyclic systems in academic and industrial research laboratories.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development and quality control in API manufacturing.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic and pharmacodynamic properties of lead compounds.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring a specific, complex molecular scaffold.

Basic Information

Product Name	4H-Pyrimido[2,1-A]Isoquinoline-3-Carboxylic Acid, 6,7-Dihydro-10-(2-Methyl-1-Oxopropoxy)-4-Oxo-
CAS No.	69301-13-9
Molecular Formula	C₁₉H₁₈N₂O₅
Molecular Weight	354.36 g/mol
Synonyms	10-(2-Methylpropanoyloxy)-6,7-dihydro-4-oxo-4H-pyrimido[2,1-a]isoquinoline-3-carboxylic acid; 6,7-Dihydro-10-(2-methyl-1-oxopropoxy)-4-oxo-4H-pyrimido[2,1-a]isoquinoline-3-carboxylic acid; 4H-Pyrimido[2,1-a]isoquinoline-3-carboxylic acid, 6,7-dihydro-10-(2-methyl-1-oxopropoxy)-4-oxo-; 69301-13-9; Pivaloyl ester derivative of DHPC; Isoquinolinopyrimidine carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored accordingly to maintain stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.