Description

n-Acetyl-S-(1-Phenyl-2-Hydroxyethyl)-L-Cysteine is a specialized chiral cysteine derivative of significant interest in biochemical research and pharmaceutical development. This compound serves as a crucial intermediate and reference standard in the study of metabolic pathways, particularly those involving the conjugation and detoxification of xenobiotics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories engaged in advanced life science studies. Its defined structure makes it valuable for method development, calibration, and as a building block in synthetic chemistry.

Application

• Biomarker Research: Used as a reference standard for the identification and quantification of mercapturic acid metabolites in biological samples, aiding in exposure and metabolic studies.
• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly those targeting specific enzymatic pathways.
• Toxicology & Metabolism Studies: Essential for investigating the metabolic fate of styrene and related aryl compounds, helping to elucidate detoxification mechanisms.
• Analytical Method Development: Employed as a high-purity standard to validate and calibrate analytical methods such as HPLC, LC-MS, and GC-MS in contract research organizations (CROs) and quality control labs.
• Bioconjugation Chemistry: Acts as a protected cysteine derivative for the synthesis of peptides or protein conjugates in biochemical research.

Basic Information

Product Name	n-Acetyl-S-(1-Phenyl-2-Hydroxyethyl)-L-Cysteine
CAS No.	69278-53-1
Molecular Formula	C₁₃H₁₇NO₄S
Molecular Weight	283.34 g/mol
Synonyms	N-Acetyl-S-(1-phenyl-2-hydroxyethyl)cysteine; N-Acetyl-S-(1-Phenyl-2-Hydroxyethyl)-L-Cysteine; L-Cysteine, N-acetyl-S-(1-phenyl-2-hydroxyethyl)-; N-Acetyl-S-(1-Phenyl-2-hydroxyethyl)cysteine; Acetylcysteine, S-(1-phenyl-2-hydroxyethyl)-, L-; S-(1-Phenyl-2-hydroxyethyl)-N-acetyl-L-cysteine; Mercapturic acid derivative of styrene; Styrene mercapturic acid (acetylated)
EINECS	Contact for details

Quality Control

Our n-Acetyl-S-(1-Phenyl-2-Hydroxyethyl)-L-Cysteine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure identity, potency, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters such as assay, enantiomeric purity, and related substances. We support research and development with material traceability and data integrity aligned with GLP (Good Laboratory Practice) principles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of water vapor. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.