Description

Valyl-Prolyl-Glycyl-Valyl-Glycine Polypeptide is a synthetic pentapeptide sequence of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial building block and model substrate for studying enzyme kinetics, peptide stability, and structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in proteomics, drug discovery, and advanced material science.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays, particularly for studying proteases like collagenases and matrix metalloproteinases (MMPs).
• Pharmaceutical Development: Serves as a key intermediate or model compound in the discovery and optimization of peptide-based therapeutics targeting various diseases.
• Cosmeceutical Research: Investigated for potential applications in skincare formulations aimed at modulating collagen synthesis and skin remodeling processes.
• Academic Studies: Employed in university and institutional labs for teaching and research on peptide synthesis, purification, and analytical characterization techniques.
• Proteomics & Biomarker Discovery: Acts as a reference peptide in mass spectrometry-based proteomic studies for method development and calibration.
• Material Science: Explored as a component in the design of bio-inspired materials and hydrogels due to its specific amino acid sequence.

Basic Information

Product Name	Valyl-Prolyl-Glycyl-Valyl-Glycine Polypeptide
CAS No.	69221-84-7
Molecular Formula	C22H36N6O7
Molecular Weight	496.56 g/mol
Synonyms	VPGVG; VPGVG Peptide; Pentapeptide VPGVG; L-Valyl-L-prolyl-glycyl-L-valylglycine; Val-Pro-Gly-Val-Gly; VPGFG (common alternate); Poly(VPGVG); (Val-Pro-Gly-Val-Gly)n
EINECS	Contact for details

Quality Control

Our Valyl-Prolyl-Glycyl-Valyl-Glycine Polypeptide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay by HPLC, peptide content, and related substances. Our quality commitment aligns with cGMP principles for research-grade materials, ensuring reliable and reproducible performance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture. For extended storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.