Description

1-(3-Amino-4-Fluorophenyl)Pyrrolidin-2-One is a high-purity fluorinated pyrrolidinone derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. Its molecular structure, featuring both an aromatic amine and a lactam ring, makes it essential for constructing complex molecules with targeted biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals in laboratory and industrial settings.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.
• Bioconjugation & Probe Development: The aromatic amine group allows for use in creating fluorescent probes or bioconjugates for diagnostic and research applications.

Basic Information

Product Name	1-(3-Amino-4-Fluorophenyl)Pyrrolidin-2-One
CAS No.	69131-57-3
Molecular Formula	C10H11FN2O
Molecular Weight	194.21 g/mol
Synonyms	3-Amino-4-fluoro-1-(2-oxopyrrolidin-1-yl)benzene; 1-(3-Amino-4-fluorophenyl)-2-pyrrolidinone; 4-Fluoro-3-(2-oxopyrrolidin-1-yl)aniline; 1-(3-Amino-4-fluorophenyl)pyrrolidin-2-one; 69131-57-3; 3-Amino-4-fluoro-N-phenyl-2-pyrrolidinone; 4-Fluoro-3-(pyrrolidin-1-yl)aniline-2-one
EINECS	Contact for details

Quality Control

Our 1-(3-Amino-4-Fluorophenyl)Pyrrolidin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.