Description

2-Pyrimidinamine, 5-(Trifluoromethyl)- (9Ci) CAS NO 69034-08-8 is a high-purity, trifluoromethyl-substituted pyrimidine derivative, a privileged scaffold in modern synthetic chemistry. This compound is valued for its role as a versatile and critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules with enhanced biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or molecular semiconductors.
• Chemical Biology: Employed as a probe or labeling reagent in medicinal chemistry and biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial research quantities.

Basic Information

Product Name	2-Pyrimidinamine, 5-(Trifluoromethyl)- (9Ci)
CAS No.	69034-08-8
Molecular Formula	C5H4F3N3
Molecular Weight	163.10 g/mol
Synonyms	5-(Trifluoromethyl)pyrimidin-2-amine; 2-Amino-5-(trifluoromethyl)pyrimidine; 5-(Trifluoromethyl)-2-pyrimidinamine; 5-Trifluoromethyl-2-pyrimidinamine; 2-Pyrimidinamine, 5-(trifluoromethyl)-; 69034-08-8; 5-Trifluoromethylpyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Production follows cGMP principles where applicable, and every batch is analyzed to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing specifications such as assay (HPLC), related substances, and residual solvents. Our quality system is designed to meet the exacting standards of pharmaceutical and agrochemical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.