Description

Phenol, 5-(1,1-Dimethylethyl)-2-Fluoro- is a fluorinated phenolic compound characterized by a tert-butyl substituent, offering a unique combination of steric bulk and electronic effects. This specialty intermediate is valued for its role in modifying molecular properties, particularly in the synthesis of advanced materials and active pharmaceutical ingredients. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated phenolic motifs for enhanced bioavailability or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom and phenolic group contribute to biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or functionalization agent in the development of specialty polymers, resins, and liquid crystals with tailored thermal and optical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to create novel ligands that modulate metal center reactivity.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, material science, and synthetic methodology studies in academic and industrial laboratories.

Basic Information

Product Name	Phenol, 5-(1,1-Dimethylethyl)-2-Fluoro-
CAS No.	68997-57-9
Molecular Formula	C10H13FO
Molecular Weight	168.21 g/mol
Synonyms	2-Fluoro-5-tert-butylphenol; 5-tert-Butyl-2-fluorophenol; 2-Fluoro-5-(tert-butyl)phenol; 5-(tert-Butyl)-2-fluorophenol; 1-tert-Butyl-3-fluoro-4-hydroxybenzene; 2-Fluoro-5-(1,1-dimethylethyl)phenol; Phenol, 2-fluoro-5-(1,1-dimethylethyl)-
EINECS	Contact for details

Quality Control

Our production of Phenol, 5-(1,1-Dimethylethyl)-2-Fluoro- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure consistency and meet the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.