Description

5''-Isobromocriptine is a specialized brominated derivative of the ergot alkaloid class, serving as a key intermediate in advanced pharmaceutical synthesis. This compound is valued for its role in the research and development of novel therapeutic agents, particularly those targeting neurological and endocrine pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on neuropharmacology and drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel dopamine receptor agonists and other central nervous system (CNS) active compounds.
• Research & Development: Used in academic and industrial laboratories for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Preclinical Studies: Employed in the investigation of pharmacological profiles and metabolic pathways of bromocriptine analogs.

Basic Information

Product Name	5''-Isobromocriptine
CAS No.	68944-89-8
Molecular Formula	C32H40BrN5O5
Molecular Weight	654.60 g/mol
Synonyms	5''-Bromocriptine; 2-Bromoergocryptine; 2-Bromo-α-ergocryptine; 2-Bromocryptine; 2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'α-(2-methylpropyl)ergotaman-3',6',18-trione; (5'α)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)ergotaman-3',6',18-trione; Isobromocriptine; 5''-Bromo-α-ergocryptine
EINECS	Contact for details

Quality Control

Our 5''-Isobromocriptine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.