Description

Angiotensin II, Sar(1,7)- is a potent and selective peptide analog of the endogenous vasoconstrictor Angiotensin II, designed for advanced biochemical and pharmacological research. This modified peptide is critical for studying the renin-angiotensin system (RAS), receptor binding mechanisms, and cardiovascular physiology. It serves as an essential tool for pharmaceutical R&D, academic laboratories, and diagnostic kit manufacturers focused on hypertension, heart failure, and metabolic disorder research.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of the renin-angiotensin-aldosterone system (RAAS) and its role in blood pressure regulation.
• Pharmacological Studies: Employed in receptor binding assays (AT1 and AT2 receptors) and functional studies to evaluate antagonist/agonist activity and signal transduction pathways.
• Pharmaceutical Development: Serves as a key intermediate or reference compound in the discovery and development of novel cardiovascular therapeutics and diagnostic agents.
• Academic & Clinical Research: Utilized in university and hospital laboratories for investigating the pathophysiology of hypertension, heart failure, kidney disease, and other RAS-related disorders.
• Diagnostic Manufacturing: Acts as a critical component in the production of immunoassay kits, ELISA tests, and other in vitro diagnostic (IVD) reagents for measuring angiotensin peptides.

Basic Information

Product Name	Angiotensin II, Sar(1,7)-
CAS No.	68941-20-8
Molecular Formula	C47H68N14O11S
Molecular Weight	1021.2 g/mol
Synonyms	Saralasin; [Sar1,Ala8]-Angiotensin II; 1-Sarcosine-8-alanine-angiotensin II; Sar1,Ala8-Ang II; Angiotensin II antagonist; Sarcosyl1,Alanyl8-Angiotensin II; [Sar1, Ala8]Ang II; P113
EINECS	Contact for details

Quality Control

Our Angiotensin II, Sar(1,7)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade specifications and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.