Description

Sodium 5-Oxo-D-Prolinate is the sodium salt of 5-oxo-D-proline, a derivative of the amino acid proline. This compound is a key chiral intermediate and building block in the synthesis of more complex molecules, particularly in the pharmaceutical and fine chemical industries. It is primarily utilized by research institutions and manufacturers involved in producing active pharmaceutical ingredients (APIs), peptide synthesis, and advanced biochemical research.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Synthesis: Used in the preparation of modified peptides and peptidomimetics where the 5-oxoproline (pyroglutamic acid) structure is required.
• Biochemical Research: Serves as a substrate or standard in enzymatic studies and metabolic pathway research.
• Fine Chemical Synthesis: An intermediate in the production of specialty chemicals, flavors, and fragrances.
• Cosmetic Ingredients: Potential use in the synthesis of certain moisturizing or skin-conditioning agents.

Basic Information

Product Name	Sodium 5-Oxo-D-Prolinate
CAS No.	68766-98-3
Molecular Formula	C5H6NNaO3
Molecular Weight	151.10 g/mol
Synonyms	Sodium (2S)-5-oxopyrrolidine-2-carboxylate; Sodium D-Pyroglutamate; Sodium (D)-Pyroglutamate; D-Pyroglutamic Acid Sodium Salt; (S)-Pyroglutamic Acid Sodium Salt; 5-Oxo-D-proline Sodium Salt; L-Glutamic acid 5-lactam sodium salt (D-form)
EINECS	Contact for details

Quality Control

Our Sodium 5-Oxo-D-Prolinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, enantiomeric purity, and impurity profiles. Specifications can be tailored to meet pharmaceutical (GMP), research, and commercial grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation and caking.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% (D-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition (Sulfated Ash)	Conforms
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.