Description

4-Chloro-2-(4-Methoxyphenyl)Pyrimidine is a versatile pyrimidine derivative, a key heterocyclic building block prized for its functional group handles. This compound matters for its role as a crucial synthetic intermediate in the development of more complex molecules. It is needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce diverse functional groups.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	4-Chloro-2-(4-Methoxyphenyl)Pyrimidine
CAS No.	68535-54-6
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	4-Chloro-2-(4-methoxyphenyl)pyrimidine; 2-(4-Methoxyphenyl)-4-chloropyrimidine; 4-Chloro-2-(p-methoxyphenyl)pyrimidine; 4-Chloro-2-(4'-methoxyphenyl)pyrimidine; Pyrimidine, 4-chloro-2-(4-methoxyphenyl)-; 68535-54-6 (CAS); 4-Cl-2-(4-MeO-Ph)-Pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(4-Methoxyphenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), physical characteristics, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.