Description

Z-Lys(Ac)-Oh Dcha is a protected amino acid derivative, specifically the Nα-Z-protected and Nε-acetylated lysine compound as a dicyclohexylamine (DCHA) salt. This compound is a critical building block in solid-phase peptide synthesis (SPPS), offering orthogonal protection strategies essential for constructing complex peptides and bioconjugates. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key intermediate for the controlled incorporation of lysine residues with orthogonal side-chain protection (Nε-Acetyl).
• Pharmaceutical Research: Synthesis of peptide-based drug candidates, hormones, and enzyme inhibitors where specific lysine modification is required.
• Bioconjugation: Preparation of peptide tags, linkers, and carriers for antibody-drug conjugates (ADCs) and other targeted therapies.
• Biochemical Tool Development: Production of substrates, standards, and probes for enzymatic assays and proteomics research.
• Material Science: Synthesis of peptide-polymer hybrids and bio-inspired materials.

Basic Information

Product Name	Z-Lys(Ac)-Oh Dcha
CAS No.	68223-09-6
Molecular Formula	C28H45N3O5
Molecular Weight	503.68 g/mol
Synonyms	Nα-Carbobenzoxy-Nε-acetyl-L-lysine dicyclohexylamine salt; Z-Lys(Ac)-OH·DCHA; CBZ-Lys(Ac)-OH DCHA salt; N6-Acetyl-N2-[(benzyloxy)carbonyl]-L-lysine dicyclohexylamine salt; (2S)-6-Acetamido-2-[(phenylmethoxy)carbonylamino]hexanoic acid - dicyclohexylamine (1:1); Benzyl N-{N6-acetyl-N2-[(benzyloxy)carbonyl]-L-lysyl}carbamate dicyclohexylamine salt; Protected L-Lysine DCHA Salt
EINECS	Contact for details

Quality Control

Our Z-Lys(Ac)-Oh Dcha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.